Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone-induced dickkopf-1 expression in human hair dermal papilla cells
BMB Rep. 2010 Oct;43(10):688-92. Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosterone-induced dickkopf-1 expression in human hair dermal papilla cells. Kwack MH, Ahn JS, Kim MK, Kim

Topical realted to Dkk 1 supression
http://www.renokin.com/index.php?pgname=home/sub_overview I think this used in combination with Calcium Threonate would have a synergistic effect? CS - A>R - any thoughts? Unless I am mistaken, wasn't Nid getting this stuff? I definitely want

Brain Health supplements(CS please write an article about this on healthyfixx)
http://www.youtube.com/watch?v=4WjJy0yvMiM I saw this video and this is a more ample discussion http://www.superhumanradio.com/shr-875-life-extension-latest-for-2012-plus-paleo-nutrition-primer-101-for-beginners.html where they talk about magnesium l

OT: Neurogen model of depression- Brain atrophy- how to reverse it?
In contrast to the monoamine theory of depression, the neurogenic model described in the following paragraph talks about long term brain morphology... which includes nerve cell death and dendritic atrophy in the hippocampus, as well as atrophy of the

Hair Loss article on HealthyFixx
Danny Roddy wrote up an article about his thoughts on diet's role in hair loss and Brian added a counterpoint about the importance of supplementing with antioxidants, vitamins, and minerals. Many of you know their views on the subject but it's a worthwhil

Magnesium
What magnesium source is recommended? I use Megafoods (http://www.megafood.com/mineral-formulas/magnesium) and RealSalt (http://www.realsalt.com/media/files/realsalt_analysis.pdf) about 1/4-1/2 tsp a day Is this enough? The pill makes my stool

My Hair (Progress)
I just wanted to report that lately, I can't believe how incredibly soft and thicker my hair has been. A combination of getting on the Lithium/DMSO rinse (5% Lithium Chloride, 8% DMSO), and upgrading my helmet to 280 diodes from 80, has made a very

Supplements in the very long term?
I began to take supps at the beginning of this year, and when I see the benefits it brings me (more hair, clear skin, high sex drive, more energy etc.), I think I'll take them all my life, even if it costs me 500€ a year, I don't care. What effects will

PQQ pyrroloquinoline quinone
CS and others....what is your take on PQQ? Even more mitocondria support? http://www.lef.org/magazine/mag2011/feb2011_Generate-Fresh-Mitochondria-with-PQQ_01.htm will enhance r-lipoic and l-carnitine effects further???

CS - Frontal / Vertex / Diffuse thin
Any evidence or experience you have with these types of hairloss? I know frontal hairloss can be testosterone driven... or stress... Vertex usually long term diet / DHT can cause problems... I wonder if there is any epidemiological info on the

Curcumin, Apigenin promote hair growth
Abstract Androgen-inducible transforming growth factor β (TGF-β1) derived from dermal papilla cells (DPCs) is a catagen inducer that mediates hair growth suppression in androgenetic alopecia (AGA). In this study, a cell-based assay system was

Question for CS regarding DKK-1
CS, I've been slowly reading through all of your posts which were recently compiled into one mega-post. At this point I am just scratching the surface. I read the part about DHT causing upregulation of the DKK-1 gene in balding scalps. I found a

Anti-oxidant supplementation potentially blunts the insulin-sensitizing effects of weight-trianing
1. Properly Time Your Antioxidant Intake When I first got interested in weight lifting and bodybuilding I read stories about professional bodybuilders and their tackle boxes full of supplements and vitamins. Most notably, Skip La Cour would keep one in

Swanson GreenFoods Formulas Ecklonia Cava Extract - the real deal???
hi all, About to restock my 6 mnth supply of Ecklonia cava and it seems swanson ecklonia, for $7 a bottle, has appeared back in stock. I'm considering purchasing a few bottles but of course I am hesitant when it is so cheap; yet I have always found

L-ascorbic acid 2-phosphate represses dickkopf-1 expression
Have we discussed this study earlier? If so I obviously missed it. I probably did L-ascorbic acid 2-phosphate represses the dihydrotestosterone-induced dickkopf-1 expression in human balding dermal papilla cells Abstract Recent studies suggeste